November 2018, reMYND investment
reMYND NV, founded in 2002 as a spin-off from the University of Leuven, drives the development of disease-modifying treatments against Alzheimer’s, Parkinson’s, diabetes, and other orphan protein misfolding disorders. To fulfil this mission reMYND is organised as two independently managed business entities entailing a Drug Discovery & Development unit and the Contract Research Organization (CRO).
reMYND’s most advanced own program, ReS19, restores calcium homeostasis in Alzheimer’s, a process central in the disease cascade leading to neuronal demise and build-up of plaques and tangles. By targeting the disease in its tracks, ReS19 combines the best of both worlds: delivering a more robust immediate symptomatic benefit on synaptic plasticity, cognition and cerebrospinal biomarkers, while in the longer-term preventing build-up of plaques and neuronal loss.
reMYND’s diabetes program ReS39 sustains and increases the endogenous insulin production capacity and insulin signalling in animal models of diabetes, providing fast symptomatic relief combined with durability. In addition, ReS39 reduces liver weight and its triglyceride content, making it potentially also relevant for NASH and the metabolic syndrome. The program has previously shown a similar protective effect on dopamine producing neurons in Parkinson’s mice, the most common motor disorder.
In addition, reMYND’s in-vivo Contract Research Organization (CRO) helps its clients to assess the pharmacokinetics, -dynamics and efficacy of their experimental treatments against Alzheimer’s disease in reMYND’s proprietary mouse models. Our mission is to be a strategic partner for our clients and help them identify the most promising set-up to assess potential effects. Given the extensive experience fully focused on Alzheimer’s
disease, reMYND’s CRO can contribute its expertise for every type of Alzheimer treatment in any form of application. The CRO is serving 6 of the top 10 pharmaco’s worldwide and its client-base covers the US, Europe and Japan. The CRO has provided in-vivo proof-of-concept data for several candidate drugs that reMYND’s clients currently have in clinical development.
reMYND has been substantially supported by grants from VLAIO/IWT (Flanders, Belgium) and from the Michael J Fox Foundation.
For more information, contact reMYND at , + 32 16 75 14 20 or visit www.remynd.com
Korys is a family-owned holding company that on the one hand focuses on direct investments in non-listed companies, and on the other hand also manages a portfolio of listed investments. Today, it has more than EUR 4 billion of assets under management, among which a significant participation in Colruyt Group, a leading retail company in Belgium and France. Investment decisions are taken with a long-term perspective on the basis of economic, ecological and social merit. Korys aims to create sustainable value through a diversified portfolio of investments and focuses on investment themes in which it has built substantial expertise, such as “Conscious Consumer”, “Medical Revolution”, “Energy Transition”, “Leadership in Retail”, “Resource Revolution” and “Future-proof Real Estate”. Korys has a team of more than 20 professionals based in Belgium and Luxembourg.